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Nature - 1 day 15 hours agoThe capacity of hippocampal circuits to transform inputs into downstream outputs is fundamental to navigation and memory, yet the circuit-level mechanisms that enable this flexibility in adapting to experience remain unclear. Here we approach this problem by performing large-scale (up to 1,024 channel) recordings across the hippocampal–retrosplenial cortex (RSC) circuit in behaving mice, enabling simultaneous access to spiking activity in dentate gyrus (DG), CA3, CA2, CA1 and RSC. On the basis...
Nature - 1 day 15 hours agoOrgan intrinsic nervous systems (OINSs) are critical components of the body–brain axis and coordinate visceral organ function with systemic physiological control1–7. Despite their importance, how these distinct neural architectures arise from a common neural crest cell origin has remained unclear. Here we present a systems-level, cross-organ analysis of OINS development, integrating lineage tracing, 3D imaging, single-cell transcriptomics and genetic perturbations across the heart, pancreas...
This sponsored article is brought to you by Ampace . As AI workloads grow to gigascale levels, the global data center industry has hit a hidden physical wall. The real bottleneck is no longer just the thermal limit of the chip or the capacity of the cooling system it is the dynamic resilience of the power chain. Modern AI computing clusters, driven by massive GPU clusters, generate high-frequency, abrupt, and synchronized spikey pulse loads. As rack densities soar beyond 100 kW, these fluctuations...
Retraction Watch - 2 days 1 min agoDaniel Bar-Shalom, a pharmacist at the University of Copenhagen, was incensed. He'd been asked to review a manuscript by Muhammad Imran Qadir, an associate professor at Bahauddin Zakariya University in Multan, Pakistan. According to his institution's website, Qadir was the "top pharmaceutical scientist" in the country. But Bar-Shalom thought the introduction to the paper felt … Continue reading Reviewer finds top pharmaceutical scientist' has a self-citation problem...
Popular Mechanics - 2 days 2 hours agoThe same plaster used in art and architecture also helped keep the deceased intact for years.
What's the animal lookalike? The post Name the orchid: Can you guess what animal these flowers are named after? appeared first on How It Works .
More than 200 drugs in the pipeline for ALS are stuck in a system that favors big, slow-moving pharmaceutical companies.
Workers at Agresti Calf Ranch in the Central Valley also were spotted removing animals' horns, apparently without anesthesia.
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